ODCs

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1 OMIM reference -
1 associated gene
12 signs/symptoms

PROTEIN INTERACTIONS: 1
COMMON SIGNS: 1

1 OMIM reference -
1 associated gene
10 signs/symptoms

Alpha-thalassemia - myelodysplastic syndrome

Papilloma of choroid plexus


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	ATRX	(0.63)	TP53

Citations in the biomedical literature:

Alpha-thalassemia - myelodysplastic syndrome		Papilloma of choroid plexus
	Synonym(s): - ATMDS - Acquired HbH disease - Acquired hemoglobin H disease		Synonym(s): (no synonyms)

	Classification (Orphanet): - Rare genetic disease - Rare hematologic disease		Classification (Orphanet): - Rare neurologic disease - Rare oncologic disease

	Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -		Classification (ICD10): - Neoplasms -

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: adulthood Average age of death: elderly Type of inheritance: sporadic		Epidemiological data: (no data available)

	External references: 1 OMIM reference - No MeSH references		External references: 1 OMIM reference - 1 MeSH reference: D020288

Alpha-thalassemia - myelodysplastic syndrome		Papilloma of choroid plexus
	Very frequent - Asthenia / fatigue / weakness - Microcytic anemia - Myelodysplastic syndrome - Polynuclear cells / neutrophils anomalies / neutropenia - Thrombocytopenia / thrombopenia Frequent - Bruisability - Hemorrhage / hemorrhagic syndrome / excessive / long-lasting bleeding - Respiratory distress / dyspnea / respiratory failure / lung volume reduction Occasional - Acute leukemia - Immunodeficiency / increased susceptibility to infections / recurrent infections - Splenomegaly		Very frequent - Autosomal recessive inheritance - Central nervous system / peripheral nerves neoplasm / tumor / carcinoma / cancer - Hydrocephaly - Structural anomalies of the nervous system Occasional - Hemiplegia / diplegia / hemiparesia / limb palsy - Hypertonia / spasticity / rigidity / stiffness - Intellectual deficit / mental / psychomotor retardation / learning disability - Mild visual loss / impaired visual acuity - Seizures / epilepsy / absences / spasms / status epilepticus